RNA Polymerase II Pre-transcription Events

Formation of TC-NER Pre-Incision Complex

Transcription-Coupled Nucleotide Excision Repair (TC-NER)

Gap-filling DNA repair synthesis and ligation in TC-NER

tRNA modification in the nucleus and cytosol

Synthesis of wybutosine at G37 of tRNA(Phe)

IL-6-type cytokine receptor ligand interactions

rRNA modification in the nucleus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol

TP53 Regulates Transcription of Cell Cycle Genes

TP53 Regulates Transcription of DNA Repair Genes

Metal sequestration by antimicrobial proteins

Signaling by moderate kinase activity BRAF mutants

Signaling by high-kinase activity BRAF mutants

RAS signaling downstream of NF1 loss-of-function variants

Paradoxical activation of RAF signaling by kinase inactive BRAF

TP53 Regulates Transcription of Genes Involved in Cytochrome C Release

TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain

TP53 Regulates Transcription of Caspase Activators and Caspases

TP53 Regulates Transcription of Death Receptors and Ligands

Ion influx/efflux at host-pathogen interface

TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest

TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain

TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest

Regulation of TP53 Activity through Phosphorylation

Regulation of TP53 Activity through Acetylation

Regulation of TP53 Activity through Association with Co-factors

Regulation of TP53 Activity through Methylation

Regulation of TP53 Expression and Degradation

RNA polymerase II transcribes snRNA genes

Retrograde transport at the Trans-Golgi-Network

Intra-Golgi and retrograde Golgi-to-ER traffic

PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling

Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Assembly of the ORC complex at the origin of replication

CDC6 association with the ORC:origin complex