Defective factor IX causes thrombophilia

Defective cofactor function of FVIIIa variant

Defective F9 variant does not activate FX

Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants

Signaling by PDGFRA extracellular domain mutants

Diseases of DNA Double-Strand Break Repair

Translation of Replicase and Assembly of the Replication Transcription Complex

SARS-CoV-1 Genome Replication and Transcription

Signaling by CSF1 (M-CSF) in myeloid cells

Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC)

Microbial modulation of RIPK1-mediated regulated necrosis

Aberrant regulation of mitotic exit in cancer due to RB1 defects

Aberrant regulation of mitotic cell cycle due to RB1 defects

Transcriptional regulation of testis differentiation

SARS-CoV-1 targets PDZ proteins in cell-cell junction

SARS-CoV-1-mediated effects on programmed cell death

SARS-CoV-1 activates/modulates innate immune responses

Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC)

SARS-CoV-2 Genome Replication and Transcription

Defective homologous recombination repair (HRR) due to BRCA2 loss of function

Defective homologous recombination repair (HRR) due to BRCA1 loss of function

Defective homologous recombination repair (HRR) due to PALB2 loss of function

STAT3 nuclear events downstream of ALK signaling

STAT5 activation downstream of FLT3 ITD mutants

Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function

Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function

SARS-CoV-2 activates/modulates innate and adaptive immune responses

SARS-CoV-2 targets PDZ proteins in cell-cell junction

FLT3 signaling through SRC family kinases

Regulation of HMOX1 expression and activity

Impaired BRCA2 translocation to the nucleus

Signaling by Rho GTPases, Miro GTPases and RHOBTB3

Sensory perception of sweet, bitter, and umami (glutamate) taste

Signaling by ALK fusions and activated point mutants

Nuclear events stimulated by ALK signaling in cancer