SHOC2 M1731 mutant abolishes MRAS complex function

Gain-of-function MRAS complexes activate RAF signaling

Defective Intrinsic Pathway for Apoptosis

Drug-mediated inhibition of MET activation

SARS-CoV-1 modulates host translation machinery

SARS-CoV-1 targets host intracellular signalling and regulatory pathways

TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation

MyD88 dependent cascade initiated on endosome

IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation

Expression and translocation of olfactory receptors

Drug-mediated inhibition of CDK4/CDK6 activity

SARS-CoV-2 modulates host translation machinery

N-glycan antennae elongation in the medial/trans-Golgi

SARS-CoV-2 targets host intracellular signalling and regulatory pathways

Reactions specific to the complex N-glycan synthesis pathway

MyD88 cascade initiated on plasma membrane

Uptake of dietary cobalamins into enterocytes

Epithelial-Mesenchymal Transition (EMT) during gastrulation

Regulation of CDH11 Expression and Function

Regulation of Homotypic Cell-Cell Adhesion

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Diseases of mitochondrial beta oxidation

Regulation of CDH11 mRNA translation by microRNAs

GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2

Regulation of Expression and Function of Type II Classical Cadherins

Regulation of CDH19 Expression and Function

NPAS4 regulates expression of target genes

Formation of WDR5-containing histone-modifying complexes

SUMOylation of nuclear envelope proteins

NFE2L2 regulating inflammation associated genes

NFE2L2 regulates pentose phosphate pathway genes

NFE2L2 regulating MDR associated enzymes

NFE2L2 regulating ER-stress associated genes

M-decay: degradation of maternal mRNAs by maternally stored factors

Z-decay: degradation of maternal mRNAs by zygotically expressed factors