Respiratory Syncytial Virus Infection Pathway

Respiratory syncytial virus (RSV) attachment and entry

Assembly and release of respiratory syncytial virus (RSV) virions

Respiratory syncytial virus (RSV) genome replication, transcription and translation

Chromatin modifications during the maternal to zygotic transition (MZT)

Replacement of protamines by nucleosomes in the male pronucleus

Defects of platelet adhesion to exposed collagen

Regulation of MITF-M-dependent genes involved in pigmentation

Regulation of MITF-M-dependent genes involved in apoptosis

Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7

Regulation of MITF-M-dependent genes involved in cell cycle and proliferation

Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence

Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation

Respiratory syncytial virus genome transcription

Antigen processing: Ubiquitination & Proteasome degradation

Class I MHC mediated antigen processing & presentation

Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Factors involved in megakaryocyte development and platelet production

Evasion by RSV of host interferon responses

CDH11 homotypic and heterotypic interactions

Respiratory syncytial virus genome replication

Specification of the neural plate border

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Cellular response to mitochondrial stress

Transcriptional regulation of brown and beige adipocyte differentiation

Transcriptional regulation of brown and beige adipocyte differentiation by EBF2

Enhanced cleavage of VWF variant by ADAMTS13

Enhanced binding of GP1BA variant to VWF multimer:collagen

Defective VWF cleavage by ADAMTS13 variant

Defective binding of VWF variant to GPIb:IX:V

Maturation of TCA enzymes and regulation of TCA cycle

Regulation of MITF-M dependent genes involved in metabolism

Regulation of MITF-M dependent genes involved in invasion

Transcriptional and post-translational regulation of MITF-M expression and activity