Formation of HIV elongation complex in the absence of HIV Tat

Formation of the HIV-1 Early Elongation Complex

RNA Pol II CTD phosphorylation and interaction with CE during HIV infection

Formation of HIV-1 elongation complex containing HIV-1 Tat

Pausing and recovery of Tat-mediated HIV elongation

Abortive elongation of HIV-1 transcript in the absence of Tat

Tat-mediated HIV elongation arrest and recovery

Tat-mediated elongation of the HIV-1 transcript

Transport of Ribonucleoproteins into the Host Nucleus

Export of Viral Ribonucleoproteins from Nucleus

NEP/NS2 Interacts with the Cellular Export Machinery

Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

Regulation of Glucokinase by Glucokinase Regulatory Protein

APC/C:Cdc20 mediated degradation of Cyclin B

SCF-beta-TrCP mediated degradation of Emi1

APC/C-mediated degradation of cell cycle proteins

APC/C:Cdc20 mediated degradation of Securin

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

Cdc20:Phospho-APC/C mediated degradation of Cyclin A

Polymerase switching on the C-strand of the telomere

Telomere C-strand (Lagging Strand) Synthesis

Interactions of Vpr with host cellular proteins

Activation of ATR in response to replication stress

Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase

Regulation of APC/C activators between G1/S and early anaphase

APC/C:Cdc20 mediated degradation of mitotic proteins

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

Interactions of Rev with host cellular proteins

APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint

Cytosolic sensors of pathogen-associated DNA

Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Degradation of beta-catenin by the destruction complex

Cobalamin (Cbl, vitamin B12) transport and metabolism

A tetrasaccharide linker sequence is required for GAG synthesis

Nuclear Events (kinase and transcription factor activation)